Prostacyclin ( Prostaglandin 12 , PGI 2 ) Inhibits Platelet Adhesion and Thrombus Formation on Subendothelium
نویسنده
چکیده
Prostaglandin I2 (prostacyclin, PGI2), a subadhesion and thrombus formation on subenstance synthesized in the wall of blood dothelium was inhibited in blood containing vessels, has been previously shown to inhibit 10 nM PGI2. PGI2 appears to reduce adhesion the aggregation of platelets in Stirred plateby inhibiting platelet spreading. These findlet-rich plasma. We used a method in which ings suggest that PGI2 could regulate the segments of deendothelialized rabbit aorta deposition of platelets on vascular surare perfused at arterial shear rates with faces. human blood and found that both platelet
منابع مشابه
Prostacyclin (prostaglandin I2, PGI2) inhibits platelet adhesion and thrombus formation on subendothelium.
Prostaglandin I2 (prostacyclin, PGI2), a substance synthesized in the wall of blood vessels, has been previously shown to inhibit the aggregation of platelets in stirred platelet-rich plasma. We used a method in which segments of deendothelialized rabbit aorta are perfused at arterial shear rates with human blood and found that both platelet adhesion and thrombus formation on subendothelium was...
متن کاملProstacyclin ( Prostaglandin 12 , PGI 2 ) Inhibits Platelet Adhesion and Thrombus Formation on
Prostaglandin I2 (prostacyclin, PGI2), a subadhesion and thrombus formation on subenstance synthesized in the wall of blood dothelium was inhibited in blood containing vessels, has been previously shown to inhibit 10 nM PGI2. PGI2 appears to reduce adhesion the aggregation of platelets in Stirred plateby inhibiting platelet spreading. These findlet-rich plasma. We used a method in which ings su...
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